DNA Sequencing Companies (December 2018)

Below is a list of 40 companies who either have a DNA sequencing platform on the market, or where there’s public information that they are developing a DNA sequencing/mapping platform. There are a few cases where it’s not clear if the company is still active, I’ve tried to note this. If have any information on these companies, know of any others, or would just like to chat about sequencing companies/the sequencing market in general, feel free to email me (new at sgenomics dot org).

Disclosure: I’ve worked at a few of these companies, all the information presented here is based on public information.

Due to the width of the table, it’s best viewed on desktop.

Name Further Info Blog post Status Detection method Single mol? Chemistry Location
Apton Biosystems Company Website Blog Series A/B Optical Yes ? Pleasanton, CA
Armonica Technologies LLC Company Website Blog Seed? Optical-nanopore Yes Direct (label free) New Mexico – USA
Base4 Company Website Blog Series A+? Microdroplet/optical (+nanopore) No Pyrophosphorolysis Cambridge – UK
BGI (inc. Complete Genomics) Company website Blog IPO Optical No SBL/SBH Mountain View – USA
BioNano Genomics Company Website Blog Series D Optical Yes Nicking/fluorescent tags San Diego – USA
Caerus Molecular Diagnostics Company Website Blog Seed – 2014 Optical Yes SBS Mountain View – USA
Centrillion Company Website Blog Series B Optical No SBS on Array Palo Alto – USA
Cygnus Biosciences News Article Blog Series B Optical No SBS Beijing – China
Depixus (was Picoseq) Company Website Blog Series A Unzipping force Yes SBL/SBH/Interference Paris
Direct Genomics Company Website Blog Unknown Optical Yes SBS Shenzhen – China
DNAe (DNA Electronics) Company Website   Series A + X? ISFET No SBS (unlabelled) London – UK
Electronic Biosciences Company Website   Seed+? Protein-nanopore Yes Direct (label free)? San Diego – USA
ElectroSeq Genomeweb Article   Pre-seed? ISFET No SBS? New Mexico – USA
Esper Biosciences SBIR Note Seed? Nanopore Yes ? Ithaca, NY
Eve Biomedical Funding note Blog Series A Optical Yes SBS-like Redwood City, CA – USA
Genapsys Company Website Blog Series C Debye layer? No SBS Redwood City – USA
Genedra Biotech Ltd Company Website (dead)   Dead? Optical Unknown SBS Beijing – China
Geneseque Company Website   Pre-seed? Optical Yes SBH? Norway
Genome Surveillance, Inc. Online note   Pre-seed Unknown Yes? Restriction map? Wisconsin – USA
Illumina Company Website   IPO Optical No SBS San Diego – USA
iNanoBio Company Website Blog Seed Nanopore – FET Yes Direct Arizona – USA
inSilixa Company Website Blog Series A Optical+Other No SBS/Hybridisation Sunnyvale, CA – USA
Intelligent biosystems (Qiagen) Company Website   Acquired Optical No SBS? Netherlands
Ion Torrent (ThermoFisher) Company Website   Acquired ISFET No SBS (unlabelled) Massachusetts – USA?
Lasergen (Agilent) Company Website   Acquired Optical No SBS Texas – USA
Lightspeed Genomics Company Website   Acquired? Optical Unknown Unknown Santa Clara – USA
Molecular Research Limited (Mobious) Company Website   Seed? Alive? Molecular Resonance Sequencing Unknown Unknown Exeter – UK
Nabsys 2.0 Company Website   Series E+ Solid-state nanopore Yes hybridized tags Rhode Island – USA
NanoString Technologies Bio IT World Article   Series E+ Optical No hybridized tags Seattle – USA
Northshore Bio Company Website Blog Series A Solid-state nanopore Yes Direct (label free) Camas, WA
Omniome Company Website   Series A+ Undisclosed Undisclosed SBB San Diego – USA
OpGen Company Website   IPO Optical Yes Restriction mapping Maryland – USA
Oxford Nanopore Technologies Company Website   Series I+ Protein-nanopore Yes Direct (label free) Oxford – UK
PacBio Company Website   IPO Optical – ZMW Yes SBS Menlo Park – USA
Personal Genomics/CrackerBio Video Blog Series B Optical Semiconductor Yes SBS Taiwan
Qiagen Company Website     Optical No SBS Germany
Quantapore Company Website   Series C Optical-Nanopore Yes All bases labelled Menlo Park – USA
Quantum Biosystems Company Website   Series B Nanopore/gap Yes Direct (label free) Osaka – Japan
QuantumDX Company Website Blog Series C+ Nanowire Yes/No Tags or SBS Newcastle – UK
QuantumSi Company Website Blog ? Optical – ZMW Yes SBS Guilford, CT
ReadCoor Company Website   Series A Optical No? SBS? Cambridge, MA – USA
Roche (Genia Technologies) Company Website   Acquired Protein-nanopore Yes SBS Santa Clara – USA
Roswell Biotechnologies Company Website Blog Series A Nanogap Yes SBS-like San Diego – USA
SeqLL Company Website   Series A Optical Yes SBS Massachusetts – USA
SingularBIO Company Website   Series A? Unknown Unknown Unknown San Francisco – USA
Singular Genomics Note   Unknown Unknown Unknown Unknown San Diego – USA
Stratos Genomics Company Website Blog Series C? Nanopore (protein?) Yes Seq-by-Expansion Seattle – USA
Two Pore Guys Company Website   Series B? Solid-state nanopore Yes Unknown/Various Santa Cruz – USA
Universal Sequencing Technology Corporation Company Website Blog Seed? Nanopore Yes Various Stoughton, MA – USA
XGenomes Company Website   Seed? Optical Unknown Unknown Boston – USA

SBS: Sequencing-by-Synthesis

SBH: Sequencing-by-Hybridization

SBB: Sequencing-by-Binding