{"id":4086,"date":"2018-07-13T16:19:01","date_gmt":"2018-07-13T16:19:01","guid":{"rendered":"http:\/\/41j.com\/blog\/?p=4086"},"modified":"2021-04-10T04:16:07","modified_gmt":"2021-04-10T04:16:07","slug":"dna-sequencing-companies-july-2018","status":"publish","type":"post","link":"https:\/\/41j.com\/blog\/2018\/07\/dna-sequencing-companies-july-2018\/","title":{"rendered":"DNA Sequencing Companies (Updated May 2020)"},"content":{"rendered":"\n

Below is a list of 40+ companies who either have a DNA sequencing platform on the market, or where there’s public information that they are developing a DNA sequencing\/mapping platform. Below the main table is a list is mapping companies, many of which have sequencing related IP\/approaches. There are a few cases where it’s not clear if the company is still active, I’ve tried to note this. If have any information on these companies, know of any others, or would just like to chat about sequencing companies\/the sequencing market in general, feel free to email me (new at sgenomics dot org).<\/p>\n

Disclosure: I’ve worked at a few of these companies, all the information presented here is based on public information.<\/p>\n

Due to the width of the table, it’s best viewed on desktop.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Name<\/td>\nFurther Info<\/td>\nBlog post<\/td>\nStatus<\/td>\nDetection method<\/td>\nSingle mol?<\/td>\nChemistry<\/td>\nLocation<\/td>\n<\/tr>\n
Apton Biosystems<\/td>\nCompany Website<\/a><\/td>\n1 <\/a>2<\/a><\/td>\nSeries A\/B<\/td>\nOptical<\/td>\nYes<\/td>\n?<\/td>\nPleasanton, CA<\/td>\n<\/tr>\n
Armonica Technologies LLC<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeed?<\/td>\nOptical-nanopore<\/td>\nYes<\/td>\nDirect (label free)<\/td>\nNew Mexico – USA<\/td>\n<\/tr>\n
Base4<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries A+?<\/td>\nMicrodroplet\/optical (+nanopore)<\/td>\nNo<\/td>\nPyrophosphorolysis<\/td>\nCambridge – UK<\/td>\n<\/tr>\n
BGI (inc. Complete Genomics)<\/td>\nCompany website<\/a><\/td>\nBlog<\/a><\/td>\nIPO<\/td>\nOptical<\/td>\nNo<\/td>\nSBL\/SBH<\/td>\nMountain View – USA<\/td>\n<\/tr>\n
Caerus Molecular Diagnostics<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeed – 2014<\/td>\nOptical<\/td>\nYes<\/td>\nSBS<\/td>\nMountain View – USA<\/td>\n<\/tr>\n
Centrillion<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries B<\/td>\nOptical<\/td>\nNo<\/td>\nSBS on Array<\/td>\nPalo Alto – USA<\/td>\n<\/tr>\n
Cygnus Biosciences<\/td>\nNews Article<\/a><\/td>\nBlog<\/a><\/td>\nSeries B<\/td>\nOptical<\/td>\nNo<\/td>\nSBS<\/td>\nBeijing – China<\/td>\n<\/tr>\n
Depixus (was Picoseq)<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries A<\/td>\nUnzipping force<\/td>\nYes<\/td>\nSBL\/SBH\/Interference<\/td>\nParis<\/td>\n<\/tr>\n
Direct Genomics<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nUnknown<\/td>\nOptical<\/td>\nYes<\/td>\nSBS<\/td>\nShenzhen – China<\/td>\n<\/tr>\n
DNAe (DNA Electronics)<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries A + X?<\/td>\nISFET<\/td>\nNo<\/td>\nSBS (unlabelled)<\/td>\nLondon – UK<\/td>\n<\/tr>\n
Electronic Biosciences<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeed+?<\/td>\nProtein-nanopore<\/td>\nYes<\/td>\nDirect (label free)?<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
ElectroSeq<\/td>\nGenomeweb Article<\/a><\/td>\n <\/td>\nPre-seed?<\/td>\nISFET<\/td>\nNo<\/td>\nSBS?<\/td>\nNew Mexico – USA<\/td>\n<\/tr>\n
Element Biosciences<\/td>\nBlog<\/a><\/td>\nBlog<\/a><\/td>\nSeries A<\/td>\nOptical?<\/td>\nNo<\/td>\nSBS?<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
Esper Biosciences<\/td>\nSBIR Note<\/a><\/td>\n <\/td>\nSeed?<\/td>\nNanopore<\/td>\nYes<\/td>\n?<\/td>\nIthaca, NY<\/td>\n<\/tr>\n
Genapsys<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries C<\/td>\nDebye layer?<\/td>\nNo<\/td>\nSBS<\/td>\nRedwood City – USA<\/td>\n<\/tr>\n
Genedra Biotech Ltd<\/td>\nCompany Website (dead)<\/a><\/td>\n <\/td>\nDead?<\/td>\nOptical<\/td>\nUnknown<\/td>\nSBS<\/td>\nBeijing – China<\/td>\n<\/tr>\n
Geneseque<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nPre-seed?<\/td>\nOptical<\/td>\nYes<\/td>\nSBH?<\/td>\nNorway<\/td>\n<\/tr>\n
Illumina<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nIPO<\/td>\nOptical<\/td>\nNo<\/td>\nSBS<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
iNanoBio<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeed<\/td>\nNanopore – FET<\/td>\nYes<\/td>\nDirect<\/td>\nArizona – USA<\/td>\n<\/tr>\n
inSilixa<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries A<\/td>\nOptical+Other<\/td>\nNo<\/td>\nSBS\/Hybridisation<\/td>\nSunnyvale, CA – USA<\/td>\n<\/tr>\n
Intelligent biosystems (Qiagen)<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nAcquired<\/td>\nOptical<\/td>\nNo<\/td>\nSBS?<\/td>\nNetherlands<\/td>\n<\/tr>\n
Ion Torrent (ThermoFisher)<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nAcquired<\/td>\nISFET<\/td>\nNo<\/td>\nSBS (unlabelled)<\/td>\nMassachusetts – USA?<\/td>\n<\/tr>\n
Lasergen (Agilent)<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nAcquired<\/td>\nOptical<\/td>\nNo<\/td>\nSBS<\/td>\nTexas – USA<\/td>\n<\/tr>\n
Lightspeed Genomics<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nAcquired?<\/td>\nOptical<\/td>\nUnknown<\/td>\nUnknown<\/td>\nSanta Clara – USA<\/td>\n<\/tr>\n
Molecular Research Limited (Mobious)<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeed? Alive?<\/td>\nMolecular Resonance Sequencing<\/td>\nUnknown<\/td>\nUnknown<\/td>\nExeter – UK<\/td>\n<\/tr>\n
Northshore Bio<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries A<\/td>\nSolid-state nanopore<\/td>\nYes<\/td>\nDirect (label free)<\/td>\nCamas, WA<\/td>\n<\/tr>\n
Omniome<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries A+<\/td>\nUndisclosed<\/td>\nUndisclosed<\/td>\nSBB<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
Oxford Nanopore Technologies<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries I+<\/td>\nProtein-nanopore<\/td>\nYes<\/td>\nDirect (label free)<\/td>\nOxford – UK<\/td>\n<\/tr>\n
PacBio<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nIPO<\/td>\nOptical – ZMW<\/td>\nYes<\/td>\nSBS<\/td>\nMenlo Park – USA<\/td>\n<\/tr>\n
Personal Genomics\/CrackerBio<\/td>\nVideo<\/a><\/td>\nBlog<\/a><\/td>\nSeries B<\/td>\nOptical Semiconductor<\/td>\nYes<\/td>\nSBS<\/td>\nTaiwan<\/td>\n<\/tr>\n
Qiagen<\/td>\nCompany Website<\/a><\/td>\n <\/td>\n <\/td>\nOptical<\/td>\nNo<\/td>\nSBS<\/td>\nGermany<\/td>\n<\/tr>\n
Quantapore<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries C<\/td>\nOptical-Nanopore<\/td>\nYes<\/td>\nAll bases labelled<\/td>\nMenlo Park – USA<\/td>\n<\/tr>\n
Quantum Biosystems<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries B<\/td>\nNanopore\/gap<\/td>\nYes<\/td>\nDirect (label free)<\/td>\nOsaka – Japan<\/td>\n<\/tr>\n
QuantumDX<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries C+<\/td>\nNanowire<\/td>\nYes\/No<\/td>\nTags or SBS<\/td>\nNewcastle – UK<\/td>\n<\/tr>\n
QuantumSi<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\n?<\/td>\nOptical – ZMW<\/td>\nYes<\/td>\nSBS<\/td>\nGuilford, CT<\/td>\n<\/tr>\n
ReadCoor<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries A<\/td>\nOptical<\/td>\nNo?<\/td>\nSBS?<\/td>\nCambridge, MA – USA<\/td>\n<\/tr>\n
Roche (Genia Technologies)<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nAcquired<\/td>\nProtein-nanopore<\/td>\nYes<\/td>\nSBS<\/td>\nSanta Clara – USA<\/td>\n<\/tr>\n
Roswell Biotechnologies<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries A<\/td>\nNanogap<\/td>\nYes<\/td>\nSBS-like<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
SeqLL<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries A<\/td>\nOptical<\/td>\nYes<\/td>\nSBS<\/td>\nMassachusetts – USA<\/td>\n<\/tr>\n
Single Technologies<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeed+<\/td>\nOptical<\/td>\nYes<\/td>\nSBS?<\/td>\nStockholm – Sweden<\/td>\n<\/tr>\n
SingularBIO<\/td>\nCompany Website (dead)<\/a><\/td>\nAcquisition<\/a><\/td>\nAcquired<\/td>\nUnknown<\/td>\nUnknown<\/td>\nUnknown<\/td>\nSan Francisco – USA<\/td>\n<\/tr>\n
Singular Genomics<\/td>\nNote<\/a><\/td>\nBlog<\/a><\/td>\nSeries B<\/td>\nOptical?<\/td>\nVarious<\/td>\nVarious<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
Stratos Genomics (Roche)<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nAcquired<\/td>\nNanopore (protein?)<\/td>\nYes<\/td>\nSeq-by-Expansion<\/td>\nSeattle – USA<\/td>\n<\/tr>\n\n
Ultima Genomics<\/td>\n <\/td>\nBlog<\/a><\/td>\nSeed<\/td>\nOptical<\/td>\nNo<\/td>\nSBS<\/td>\nNewark, CA – USA<\/td>\n<\/tr>\n\n
Universal Sequencing Technology Corporation<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeed?<\/td>\nNanopore<\/td>\nYes<\/td>\nVarious<\/td>\nStoughton, MA – USA<\/td>\n<\/tr>\n
XGenomes<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeed?<\/td>\nOptical<\/td>\nUnknown<\/td>\nUnknown<\/td>\nBoston – USA<\/td>\n<\/tr>\n\n\n\n<\/tbody>\n<\/table>\n\n\n

Mapping<\/h2>\n\n\n\n\n\n\n\n\n\n
Name<\/td>\nFurther Info<\/td>\nBlog post<\/td>\nStatus<\/td>\nDetection method<\/td>\nSingle mol?<\/td>\nChemistry<\/td>\nLocation<\/td>\n<\/tr>\n
Genome Surveillance, Inc.<\/td>\nOnline note<\/a><\/td>\n <\/td>\nPre-seed<\/td>\nUnknown<\/td>\nYes?<\/td>\nRestriction map?<\/td>\nWisconsin – USA<\/td>\n<\/tr>\n
BioNano Genomics<\/td>\nCompany Website<\/a><\/td>\nBlog<\/a><\/td>\nSeries D<\/td>\nOptical<\/td>\nYes<\/td>\nNicking\/fluorescent tags<\/td>\nSan Diego – USA<\/td>\n<\/tr>\n
OpGen<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nIPO<\/td>\nOptical<\/td>\nYes<\/td>\nRestriction mapping<\/td>\nMaryland – USA<\/td>\n<\/tr>\n
Nabsys 2.0<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries E+<\/td>\nSolid-state nanopore<\/td>\nYes<\/td>\nhybridized tags<\/td>\nRhode Island – USA<\/td>\n<\/tr>\n
NanoString Technologies<\/td>\nBio IT World Article<\/a><\/td>\n <\/td>\nSeries E+<\/td>\nOptical<\/td>\nNo<\/td>\nhybridized tags<\/td>\nSeattle – USA<\/td>\n<\/tr>\n
Ontera<\/td>\nCompany Website<\/a><\/td>\n <\/td>\nSeries C?<\/td>\nSolid-state nanopore<\/td>\nYes<\/td>\nIonic?<\/td>\nSanta Cruz – USA<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

SBS: Sequencing-by-Synthesis<\/p>\n

SBH: Sequencing-by-Hybridization<\/p>\n

SBB: Sequencing-by-Binding<\/p>\n